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CBD for Dementia: How does it help?

Dementia is estimated to affect 55 million people worldwide, with the majority of cases occurring in those over 65 years of age. Such a neurodegenerative disease affects various cognitive functions and complicates daily activities.  

Cannabidiol (CBD), a non-psychoactive compound, is derived from the cannabis plant.  Studies have shown that CBD for dementia is very effective. Scientific researches point out that CBD may help to alleviate some symptoms that are pretty common among patients, such as agitation, anxiety, and sleep disturbances. Furthermore, some studies indicate that CBD could be neuroprotective and can slow down the course of the disease. 

In this article, we will discuss how CBD provides an effective alternative for treating dementia, proven by current research studies and clinical findings. We will also discuss choosing the best CBD oil and where to buy high-quality CBD oil in Canada

What is CBD?

CBD is one of the 100-plus known cannabinoids that are found in the cannabis plant. Due to it not being a psychoactive compound, contrary to THC (tetrahydrocannabinol), it does not cause a “high” because it is non-intoxicating. It has been acclaimed to hold various potential therapeutic properties, such as anti-inflammatory, antioxidant, and neuroprotective effects. 

CBD influences the endocannabinoid system, a complex cell-signalling system that regulates physiological processes like pain, mood, appetite, and memory. Owing to its influence over the ECS, CBD provides numerous health benefits, thus becoming a subject of great interest in medical research.

What is Dementia?

Dementia is a condition characterized by a progressive loss of cognitive functions because of the damage or death of brain cells. This neurodegeneration harbours different factors, including abnormal protein accumulation, vascular damage, oxidative stress, and inflammation. These pathologic changes interfere with neural communication, producing a consequent gradual decline of cognitive function and behaviour typical of dementia.

In Canada, currently, about 600,000 people have dementia, with an estimated 25,000 new cases diagnosed every year. According to statistics, 55 million people are globally affected, and this number tends to grow significantly due to an ageing population. The increased prevalence of dementia is a call for the search for treatment that is effective and preventative measures.

Benefits of Using CBD Oil for Dementia

Here are some of the mechanisms by which CBD is thought to help in managing symptoms of dementia: 

  • Anti-Inflammatory Properties: Inflammation significantly contributes to dementia progression. Chronic inflammation can lead to the destruction of brain cells and exacerbate neurodegenerative processes. The anti-inflammatory properties associated with CBD help to reduce neuroinflammation and most likely slow the progression of the disease. Various researchers have demonstrated that CBD can also inhibit the production of pro-inflammatory cytokines and reduce the activity of immune cells, further lessening brain inflammation. 
  • Neuroprotective Effects: The neuroprotective function of CBD implies it may assist in the protection of brain cells from damage. This might be helpful in preventing or slowing brain cell degeneration. CBD acts as an antioxidant, eliminating free radicals that contribute to stress and damage to brain cells. In addition, CBD has been found to support the survival and growth of new neurons.
  • Reduction of anxiety and agitation: A lot of dementia patients tend to experience anxiety, agitation, and sometimes even aggression. CBD has the potential to increase the quality of life in patients with dementia through its anxiolytic effect. By directly acting on serotonin receptors in the brain, CBD regulates mood and minimises anxiety, reducing emotional arousal. 
  • Brain Health Promotion: Some studies suggest that CBD fosters the growth of new brain cells through a process known as neurogenesis. This may go a long way toward compensating for the cell loss in conditions like dementia. It has been demonstrated that CBD upregulates the activity of brain-derived neurotrophic factor (BDNF), a protein that supports the survival and growth of neurons. This action can promote neurogenesis and enhance synaptic plasticity, maintaining cognitive function and ensuring a delay in the progression of neurodegenerative illnesses.

How Dementia Affects a Person’s Appetite? 

Dementia tremendously changes a person’s eating habits. Not only does an individual forget to eat, but they may lose interest in food. Their taste may change significantly, leading to poor eating habits, and without good nutrition intake, a lot of weight may be lost. Studies show that close to 40% of all dementia patients lose weight.

A study found in the Journal of Alzheimer’s Disease showed that physiological brain changes and psychological factors – particularly depression and anxiety – could also be the cause of appetite loss in case of dementia. 

Such challenges underscore the need for personalised nutritional strategies to ensure the well-being of dementia patients.

Current Research on CBD and Dementia

The research for CBD in dementia is still in its early stages, but some promising results seem to appear. Here’s what the research status is: 

Preclinical: Animal studies have offered valuable insights on the possible benefits of CBD for dementia. For example, a study published in the Journal of Alzheimer’s Disease in 2016 demonstrated that CBD can reverse cognitive deficits in a model of Alzheimer’s disease. 

The researchers observed reduced inflammation, oxidative stress, and neurodegeneration following CBD treatment, which enhanced cognitive functions. Other pre-clinical studies showed that CBD could rescue brain cells from damage, reduce amyloid-beta accumulation, enhance neurogenesis, and so forth, further expanding the scope for documenting a therapeutic modality for dementia. 

Clinical Trials: Human clinical trials are much more limited but have shown positive results. The Australian team conducted a small clinical trial of CBD combined with THC in patients with dementia. This combination was found to be safe and well tolerated, providing some benefit in behaviour and mood.

 Although the sample size was small, these results indicate that CBD alone and in combination with other cannabinoids should have potential therapeutic effects in managing dementia symptomatology. Further clinical trials are being conducted to determine its effect on cognitive function, behaviour, and general quality of life in dementia patients.

Case Studies and Anecdotal Evidence: Apart from preclinical and clinical research, some case studies and anecdotal evidence report that a few patients suffering from dementia show less agitation and better sleep when they use CBD-based products

Some caregivers have reported that their dementia patients displayed a reduction in anxiety and aggression when using CBD oil, leading to calmer behaviours and sleep patterns. While these reports are promising, more rigorous research is essential to verify these findings and understand the required dosages and formulations for other kinds of dementia.

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Can CBD Treat or Prevent Dementia?

At present, there is not enough proof that CBD can treat or prevent dementia, although it has been indicated that it can help in managing some of the symptoms of this condition. For example, a study published in 2019 revealed that CBD, when taken alongside THC, ameliorated agitation and irritability in such patients. 

In addition, it is effective in treating chronic pain conditions and specific psychological problems such as anxiety and depression, which are often aggravated by dementia. Although the neuroprotective properties of CBD are yet to be clarified, its interactions with the endocannabinoid system might provide symptomatic relief and enhance quality of life. 

However, more large-scale clinical trials should be done in the future to confirm its effectiveness and security for treating and preventing dementia directly.

Can CBD Help with the Mental and Physical Effects of Dementia?

CBD may provide great relief from the mental and physical symptoms of dementia, providing another hope for the effective management of this devastating illness. 

Mental and Behavioral Symptoms of Dementia

 Dementia generally reveals itself with several mental and behavioural symptoms. One of the common symptoms is depression, where one remains persistently sad and loses interest in usual activities. The other is anxiety, resulting in too much worrying and feeling tense. Agitation is also exhibited in many patients who have restlessness and emotional outbursts. These are common symptoms that CBD would work on. 

It has been found that the effects of anxiety and depression are managed by CBD through interaction with the endocannabinoid system. In other words, it is also reported that the administration of CBD with THC in patients suffering from agitation relating to dementia reduces this agitation and improves the general mood of the patients, as published in 2019. This will result in more stable emotions and improved quality of life.

Physical Symptoms of Dementia

On a physical level, dementia can lead to an inability to perform daily activities, loss of memory, and general confusion. As the disease progresses, these symptoms become very common. For instance, there is usually an issue in executing simple everyday activities, and the decline in cognitive processing is very precipitous. 

CBD might help ameliorate some of these physical symptoms. It has been proven to assist in warding off motor function disturbances related to dementia. If the coordination is increased and tremors reduced, this may help in the management of daily activities, hence overall increased mobility.

Challenges and Considerations

Although the prospect of using CBD for dementia is very exciting, some challenges and considerations need to be tackled before this can be strongly recommended for treatment:

  • Dosage: No fixed guidelines have been stipulated for the dosage of CBD. It varies widely based on a person’s weight, metabolism, and seriousness of symptoms. This should be substantiated with more studies to establish effective dosage guidelines. 

Also, the route of administration (oral, sublingual, or topical) and the formulation (oil, capsule, or cream) impact bioavailability and, hence, therapeutic effects. Personalised dosing regimens according to individuals’ characteristics and responses to treatment are needed to obtain the best possible results.

  • Drug Interactions: CBD can interact with other drugs, resulting in unwanted adverse effects. Patients should consult a healthcare provider before starting CBD if they are using other medications. CBD is metabolised by the cytochrome P450 enzyme system, which contributes to the metabolism of many drugs. 

CBD interferes in these enzymes, thereby inhibiting or inducing, changing the concentrations and efficacies of other medications like anticoagulants, antiepileptics, or antidepressants. One has to be very careful and vigilant regarding dosage adjustment for patients.

  • Long-term Effects: The long-term effects of CBD use are not yet fully understood. Although its short-term use seems safe, further studies concerning long-term safety and efficiency are needed. 

The different effects of chronic CBD use on various physiological systems must also be studied in detail, and possible risks, such as tolerance, dependence, and withdrawal, must be evaluated. Long-term studies are necessary to assess the impact of sustained CBD administration on cognition, behaviour, and overall health in dementia patients.

How to choose a high-quality CBD product?

Quality and effectiveness are critical considerations when selecting CBD products. Look for a product with clearly stated active ingredient information on the packaging, third-party testing to assure purity and efficacy, and a well-known brand with transparent sourcing and manufacturing practices. 

Here’s a quick guide to different CBD products:

Product 

Active Ingredient

Form

Use

CBD Oil

Cannabidiol (CBD)

Liquid

Oral ingestion or sublingual

CBD Gummies

Cannabidiol (CBD)

Chewable

Convenient, tasty doses

CBD Edibles

Cannabidiol (CBD)

Various

Ingestible, flavoured options

CBD Topicals

Cannabidiol (CBD)

Creams, Balms

Applied directly to the skin

CBDNorth is a trusted brand among Canadians since it produces high-quality CBD products. The ingredients and techniques used to make their products are transparent to the public, providing customers with credible and effective choices for consuming CBD.

Is CBD Safe to Use?

Through a comprehensive study, the World Health Organization has declared CBD to be safe and totally non-addictive. Most individuals who consume it don’t have any significant negative effects, and it usually has a good safety profile and is well-tolerated. However, high-quality, laboratory-tested products are always needed to ensure efficacy and prevent contamination.

Always follow recommended dosages, and before adding any new supplement, visit a medical expert if you are currently taking another prescription or have underlying health concerns to ensure that CBD may be safely and efficiently incorporated into your daily health routine.

How Do I Know How Much CBD is Right for Me?

The optimal CBD dose is determined based on body weight and metabolism. Begin with a modest amount, generally about 5-10mg, then gradually increase until you discover the optimum dose for your requirements. 

The dose also depends on how quickly a person’s metabolism works and how sensitive their condition is. A general guideline is to take 1 to 6 milligrams of CBD for every 10 pounds of body weight. Always consult a healthcare professional to determine the proper dose for your condition.

How Do I Take CBD?

CBD may be taken in various ways, each with its own benefits and customized to personal preferences and needs.

Tinctures

CBD tinctures are liquid extracts administered sublingually, which means a few drops are put under the tongue and held there for 30 to 60 seconds before ingesting. Sublingual administration enables rapid absorption into the blood, which typically results in immediate benefits.

Topicals

This category includes CBD-infused creams, balms, and lotions. Because topicals do not enter the blood circulation, they are an excellent option for those who wish to focus just on a particular area of their body and prevent systemic effects. 

Edibles

Gummies, capsules, and baked edibles are consumed through the mouth and absorbed in the digestive system. With this method, the introduction of CBD into the system is very convenient and discreet while lasting longer than tinctures or topicals. However, this method is slow for the onset of effects, usually from 30 minutes to 2 hours, because CBD takes time to be absorbed by the body. 

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Should Dementia Patients Take CBD?

CBD may hold potential benefits for patients with dementia. Studies have revealed a decrease in symptoms such as agitation, anxiety, and sleep disturbances among patients with dementia after using CBD. CBD has neuroprotective properties, thus reducing the progression of cognitive decline. 

Patients and caregivers report improved mood, lessened anxiety, and better quality of sleep. However, a medical expert should be consulted before an individual starts using CBD to ensure that it is safe and ideal for one’s condition and medical history. 

What is the Best CBD for Dementia Patients?

Good quality, full-spectrum CBD oil would be the best CBD for patients with dementia. It contains several other cannabinoids that might enhance beneficial therapeutic effects. Third-party lab testing is crucial for determining purity and potency. Consult a medical professional for dosage and formulation.

Does CBD Help Memory?

A study demonstrates CBD’s ability to improve memory through anti-inflammatory effects, brain cell protection, and stimulation of neurogenesis. It has also been demonstrated to help with some illnesses, including Alzheimer’s disease. More study is needed in this area. Before taking CBD to improve memory, always speak with a healthcare expert.

Are CBD Products Covered Under Insurance or Medicare?

The majority of insurance policies and Medicare do not include CBD-based products. This is because the FDA has only approved one drug based on CBD, Epidiolex, for conditions involving epilepsy. 

Where Can I Buy CBD for Dementia?

If you’re looking to buy CBD for dementia, consider CBDNorth. It is a trusted source of only the finest quality, purity-assured products. Made with organically grown hemp and tested rigorously for both safety and potency, users often experience benefits like reduced anxiety and improved sleep, which can be quite helpful to individuals with dementia. 

Conclusion 

CBD remains a new potential treatment for dementia, with the research still in its infancy. Though preclinical studies and anecdotal evidence point toward possible symptom modulation and overall quality-of-life improvement among patients with dementia disorders, more intensive clinical trials must be undertaken to understand the benefits further and provide guidelines on safe and efficacious use. 

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FAQs on CBD for Dementia 

Does CBD prevent brain damage?

CBD has shown some potential neuroprotective effects in preclinical studies, suggesting it might help reduce brain damage caused by conditions like stroke or traumatic brain injury. More extensive human research is needed to determine its efficacy in preventing brain damage.

What is the most effective CBD type of dementia?

 There’s no such thing as a “CBD type of dementia.” Because of its anti-inflammatory, antioxidant, and neuroprotective qualities, CBD is being studied in the treatment of symptoms related to a variety of dementias, including Alzheimer’s disease. Research is still ongoing. 

Does CBD grow brain cells?

Neurogenesis is the process of creating new brain cells, and it has been demonstrated to occur while CBD is used, particularly in the hippocampus, the brain region responsible for memory and learning. However, much more study is required before these effects and therapeutic applications can be demonstrated in humans.

How long does CBD stay in your brain?

CBD remains in the system for 2 to 5 days, although the duration can be less or more depending on the dose, regularity of use, and an individual’s metabolism. The effects on the brain, however, last several hours after consumption.

Is CBD safe for the liver?

 In moderate doses, CBD is generally safe for the liver, but in high doses or from prolonged use, liver enzyme alterations can occur. Particularly, one should talk to a health provider before using CBD if he or she has a liver condition or is using other medications. 

What CBD is best for focus? 

Full-spectrum CBD oil is believed to be best for focus because of the “entourage effect,” where several cannabinoids and terpenes work together to boost all-over benefits. Besides, higher concentrations of CBD and minimal THC in the products can help increase clarity and concentration. 

Does CBD make your mind clear? 

CBD may improve mental clarity by lowering anxiety and tension, resulting in better sleep quality. These effects can be very beneficial for improving attention and cognitive function, but they always differ across individuals. 

Can CBD boost energy? 

CBD is not well recognised as a direct energy booster. It is primarily concerned with enhancing sleep and lowering worry and tension, which naturally promotes a balanced and rejuvenated state of health, perhaps leading to increased total energy and alertness during the day.

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